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pentobarbital will reduce the level or effect of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Check Carefully (1)pentobarbital will minimize the level or effect of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Loss of, or lessened response to tofacitinib may